Detalhe da pesquisa
1.
The Regulatory Factor ZFHX3 Modifies Circadian Function in SCN via an AT Motif-Driven Axis.
Cell
; 162(3): 607-21, 2015 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26232227
2.
The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification.
PLoS Genet
; 16(4): e1008583, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32236127
3.
Zfhx3 modulates retinal sensitivity and circadian responses to light.
FASEB J
; 35(9): e21802, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34383984
4.
Functional expression of complement factor I following AAV-mediated gene delivery in the retina of mice and human cells.
Gene Ther
; 28(5): 265-276, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33750925
5.
Repair of Retinal Degeneration following Ex Vivo Minicircle DNA Gene Therapy and Transplantation of Corrected Photoreceptor Progenitors.
Mol Ther
; 28(3): 830-844, 2020 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32027843
6.
Dynamic in vivo quantification of rod photoreceptor degeneration using fluorescent reporter mouse models of retinitis pigmentosa.
Exp Eye Res
; 190: 107895, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31816293
7.
Long-term restoration of visual function in end-stage retinal degeneration using subretinal human melanopsin gene therapy.
Proc Natl Acad Sci U S A
; 114(42): 11211-11216, 2017 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28973921
8.
RNA editing as a therapeutic approach for retinal gene therapy requiring long coding sequences.
Int J Mol Sci
; 21(3)2020 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31991730
9.
Analysis of Early Cone Dysfunction in an In Vivo Model of Rod-Cone Dystrophy.
Int J Mol Sci
; 21(17)2020 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32842706
10.
Immunomodulatory Effects of Hydroxychloroquine and Chloroquine in Viral Infections and Their Potential Application in Retinal Gene Therapy.
Int J Mol Sci
; 21(14)2020 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32674481
11.
Differential roles for cryptochromes in the mammalian retinal clock.
FASEB J
; 32(8): 4302-4314, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29561690
12.
Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking.
Proc Natl Acad Sci U S A
; 113(10): 2756-61, 2016 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26903623
13.
Codon-Optimized RPGR Improves Stability and Efficacy of AAV8 Gene Therapy in Two Mouse Models of X-Linked Retinitis Pigmentosa.
Mol Ther
; 25(8): 1854-1865, 2017 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28549772
14.
Rescue of the Stargardt phenotype in Abca4 knockout mice through inhibition of vitamin A dimerization.
Proc Natl Acad Sci U S A
; 112(27): 8415-20, 2015 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26106163
15.
Absence of Neuroplastin-65 Affects Synaptogenesis in Mouse Inner Hair Cells and Causes Profound Hearing Loss.
J Neurosci
; 36(1): 222-34, 2016 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26740663
16.
Gene Therapy for Color Blindness.
Yale J Biol Med
; 90(4): 543-551, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29259520
17.
Single residue AAV capsid mutation improves transduction of photoreceptors in the Abca4-/- mouse and bipolar cells in the rd1 mouse and human retina ex vivo.
Gene Ther
; 23(11): 767-774, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27416076
18.
CNTF Gene Therapy Confers Lifelong Neuroprotection in a Mouse Model of Human Retinitis Pigmentosa.
Mol Ther
; 23(8): 1308-1319, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25896245
19.
Reversal of end-stage retinal degeneration and restoration of visual function by photoreceptor transplantation.
Proc Natl Acad Sci U S A
; 110(3): 1101-6, 2013 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23288902
20.
Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial.
Lancet
; 383(9923): 1129-37, 2014 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-24439297